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It was found out that naltrexone and bupropion combined, which can be marketed in the future as Contrave, have better weight loss results than diet and exercise alone.

Using two separate drugs to lose weight naturally can be very effective there are combinations before the FDA now awaiting approval. When dealing with fat loss and the individuals who go through it one should err on the side of caution and let the FDA do its job and demand some study be done so your public knows the side effects and perils associated with the medications before we bring them. Keep in mind that drug companies are in business to earn money and that they would say anything to keep people on his or her medications.

Researchers found out that participants investing in this drug for any year, lost excess weight within 4 weeks and have kept the extra weight off through the 56 weeks of the study. Contrave can be a combination of the drugs naltrexone and bupropion, which generally seems to reflect a new trend of weight-loss drugs that are made up of many active ingredient, which might make them far better and safer.

Combo-pilling could be the newest fad or in addition to this the newest into the future under scrutiny and for that reason it is just more publicly known in recent months, comb-pilling for losing weight has been around since the eighties. The biggest reason that using a combination of pills is starting to become popular will be the fact that at the time of right now there aren't long term prescription slimming capsules that have been approved by the FDA aside from orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications even though some of the combinations are actually rejected or have yet to be approved by the FDA.

Seizures can be a side effect with Contrave and must not be taken in individuals with seizure disorders. The drug may also raise blood pressure levels and heart rate, and must not be used in people who have a history of cardiac event or stroke in the previous six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy with the drug.

The FDA also warned that Contrave can raise blood pressure levels and heart rate and must not be used in patients with uncontrolled high hypertension, and also by you aren't heart-related and cerebrovascular (circulation system dysfunction impacting your brain) disease. Patients which has a history of heart attack or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes with a boxed warning to alert medical professionals and patients on the increased probability of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for smoking cessation.


"This may be the first drug I'm mindful of that targets the two appetite and reward centres within the brain," he explained.

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